GLP‑1 medications / Semaglutide
A once-weekly injection that quiets appetite and food noise. Your physician decides whether it fits after reviewing your history and labs, and it always comes with a health coach and one-on-one visits.
STEP 1 trial result
average body weight lost over 68 weeks on semaglutide 2.4 mg
Adults with obesity or overweight, without diabetes (Wilding et al., NEJM 2021). Averages, not a promise; everyone in the trial also made lifestyle changes.
Semaglutide acts like GLP-1, a gut hormone that signals fullness and slows how quickly the stomach empties. Most people notice they get full sooner and think about food less.
Wegovy starts low and steps up every four weeks, which is how most people avoid the worst of the nausea. Your physician may hold a step or go slower.
Once-weekly injection under the skin of the belly, thigh or upper arm, on the same day each week. 2.4 mg is the usual maintenance dose; some people stay on 1.7 mg. Schedule from the Wegovy Prescribing Information.
The most common side effects are nausea, diarrhea, vomiting, constipation, stomach pain, headache and tiredness. They are usually worst in the first weeks after each dose increase.
Less common but serious risks include pancreatitis, gallbladder problems, kidney problems from dehydration, low blood sugar with some diabetes medicines, and serious allergic reactions. Call us, or 911 in an emergency, if you have severe stomach pain that won't go away.
Wegovy® carries a boxed warning about the risk of thyroid C-cell tumors. Do not use it if you or a family member has had medullary thyroid carcinoma or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Not for use during pregnancy. Your physician reviews your history before prescribing.
Full Prescribing Information: Wegovy.
Brand-name medication is expensive without insurance, and manufacturer self-pay prices change often. Mindful Wellness is cash-pay, so we give you real numbers for the program and the medication at your free wellness consultation.
As a once-weekly injection under the skin with a prefilled pen, on the same day each week. We show you how at your first visit.
In the STEP 1 trial, adults with obesity or overweight and without diabetes who took semaglutide 2.4 mg with a reduced-calorie diet and more activity lost an average of 14.9% of body weight over 68 weeks, compared with 2.4% on placebo. Individual results vary.
In the STEP 1 extension, people who stopped semaglutide regained, on average, about two-thirds of the weight they had lost within a year. That is why coaching starts on day one and why we plan for what comes after with you.
No strict diet and no calorie counting. Your coach helps you eat enough protein, stay hydrated and choose smaller portions that fit your real week.
Not with another GLP-1 medicine such as tirzepatide. Tell your physician about everything you take, including supplements, so we can check for interactions.
Mindful Wellness is cash-pay and does not bill insurance for its programs. Program fees are FSA/HSA eligible, and we walk you through every cost up front, including medication.
Sources
This page is education, not medical advice. Mindful Wellness prescribes the medications described here.
